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Gibbs Free Energy Formula

Calculate Gibbs free energy with G = H - TS to predict if a chemical reaction will occur spontaneously.
Includes worked examples.

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The Formula

ΔG = ΔH - TΔS

Gibbs free energy determines whether a reaction will proceed spontaneously at constant temperature and pressure. A negative ΔG means the reaction is spontaneous. A positive ΔG means it is not.

Variables

SymbolMeaning
ΔGChange in Gibbs free energy (measured in kJ/mol)
ΔHChange in enthalpy — heat absorbed or released (kJ/mol)
TTemperature (measured in kelvins, K)
ΔSChange in entropy — disorder of the system (kJ/(mol·K))

Spontaneity Rules

ΔHΔSΔGSpontaneous?
Negative (exothermic)Positive (more disorder)Always negativeAlways spontaneous
NegativeNegativeDepends on TSpontaneous at low T
PositivePositiveDepends on TSpontaneous at high T
Positive (endothermic)Negative (less disorder)Always positiveNever spontaneous

Example 1

A reaction has ΔH = -92 kJ/mol and ΔS = -0.199 kJ/(mol·K) at 25°C. Is it spontaneous?

Convert temperature: T = 25 + 273.15 = 298.15 K

ΔG = ΔH - TΔS = -92 - (298.15 × -0.199)

ΔG = -92 + 59.33

ΔG = -32.67 kJ/mol (negative, so the reaction is spontaneous at 25°C)

Example 2

At what temperature does the reaction above stop being spontaneous?

Set ΔG = 0: 0 = ΔH - TΔS

T = ΔH / ΔS = -92 / -0.199

T ≈ 462 K (189°C) — above this temperature, the reaction becomes non-spontaneous

When to Use It

Use the Gibbs free energy formula to predict reaction behavior:

  • Determining if a chemical reaction will occur spontaneously
  • Finding the temperature at which a reaction becomes favorable
  • Calculating the maximum useful work a reaction can perform
  • Understanding phase transitions (melting, boiling, freezing)

Key Notes

  • Formula: ΔG = ΔH − TΔS: ΔH is enthalpy change (heat at constant pressure), T is absolute temperature (K), and ΔS is entropy change. ΔG < 0: spontaneous; ΔG > 0: non-spontaneous (requires energy input); ΔG = 0: system is at equilibrium.
  • Four sign combinations: ΔH−/ΔS+: always spontaneous (ΔG always negative). ΔH+/ΔS−: never spontaneous (ΔG always positive). ΔH−/ΔS−: spontaneous only at low T. ΔH+/ΔS+: spontaneous only at high T. Temperature determines the outcome of the latter two cases.
  • Relationship to equilibrium constant: ΔG° = −RT ln K: At standard conditions (25°C, 1 atm, 1 M concentrations). If K > 1 → ΔG° < 0 (products favored). If K < 1 → ΔG° > 0 (reactants favored). A 10-fold change in K corresponds to ~5.7 kJ/mol change in ΔG° at 25°C.
  • Connection to electrochemistry: ΔG° = −nFE°: n is moles of electrons transferred; F = 96,485 C/mol (Faraday's constant); E° is the standard cell potential. A positive cell voltage means negative ΔG° — the reaction is spontaneous and will generate electrical energy.
  • Applications: Gibbs free energy is used to predict whether a chemical reaction will proceed, determine equilibrium compositions in industrial processes, calculate maximum work obtainable from a reaction, analyze phase transitions, and understand biochemical energy coupling (ATP hydrolysis: ΔG° ≈ −30.5 kJ/mol).

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